Announcement iconContinuing Accepting Applications for Admission !!
for the Spring Semester of the Academic Year 2019/2020

Determination of Nanomolar Level of Guanine by Differential – Pluse Adsorptive Cathodic Stripping Voltammetry of its Copper (II) complex

Authors: 
R. M. Shubietah
Ali Z. Abu Zuhri
A. G. Fogg
Journal Name: 
Fresenius' Journal of Analytical Chemistry
Volume: 
348
Issue: 
11
Pages From: 
754
To: 
757
Date: 
Tuesday, November 1, 1994
Abstract: 
Guanine is determined at the 5.0×10^−10 −2.0×10^−7 mol/l level by differential-pulse adsorptive stripping voltammetry at a hanging mercury drop electrode using the reduction peak of its copper (II) complex at −0.21 V vs. Ag-AgCl electrode. The optimum analytical conditions were found to be Britton-Robinson buffer solution (pH 4.8), an accumulation potential of 0.0 V and an accumulation time of 3 min. Under these conditions, the detection limit is 5.0×10^−10 mol/l and the relative standard deviation 2.6% for 1.0×10^−7 mol/l guanine. The method is compared with the previous voltammetric methods. The presence of some purine derivatives does not interfere.