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Interactions of osteoblasts and macrophages with biodegradable and highly porous polyesterurethane foam and its degradation products

Authors: 
B Saad, S Matter, Gianluca Ciardelli, P Neuenschwander, UW Suter, GK Uhlschmid, M Welti
Journal Name: 
Journal of Biomedical Materials Research Part A
Volume: 
32
Issue: 
3
Pages From: 
355
To: 
366
Date: 
Friday, November 1, 1996
Abstract: 
The macrophage cell line J774, primary rat osteoblasts, and the osteoblast cell line MC3T3-E1 were used to examine the biocompatibility of a newly developed polyesterurethane foam and the possible use of this structure as bone-repair materials. The newly developed, biodegradable, and highly porous (pore size 100–150 μm) DegraPol/btc® polyesterurethane foam was found to exhibit good cell compatibility; the cell-to-substrate interactions induced neither cytotoxic effects nor activation of macrophages. Osteoblasts ...